Research News

Cognitive Impairment

Cognitive Changes in Parkinson’s Disease

Monday, 17 October 2016

Cognitive impairment, disturbance of memory, thinking and/or language abilities, is a non-motor symptom that can be associated with Parkinson’s. Cognitive disturbances can arise at any time in the course of Parkinson’s disease (PD) and vary widely in severity. Some people…


Common Link across Different Causes of Parkinson’s?

Friday, 7 October 2016

Parkinson’s is a variable disease — different in age of onset, experience of symptoms and cause — but a new study points to a potential common link. “Finding a common mechanism behind different suspected causes of Parkinson’s suggests that there…


Vaccine for Parkinson’s Reports Positive Results from Boost Study

Monday, 12 September 2016

New study results from Austrian biotech AFFiRiS support continued development of its vaccine against the key Parkinson’s protein alpha-synuclein. Today the company announced its “boost” follow-up study — funded with a $1.04 million grant from The Michael J. Fox Foundation…


Another Leap Forward for LRRK2 Development

Monday, 29 August 2016

Denali Therapeutics — a San Francisco biotech that launched last year focused on neurodegenerative diseases including Parkinson’s — recently announced it has licensed LRRK2 inhibitor compounds from Genentech. These drug candidates may address the dysfunction seen with LRRK2 mutations, the greatest…


Another Piece of the Alpha-synuclein Puzzle Revealed

Monday, 25 July 2016

Research on alpha-synuclein, a lead target for therapy to slow or stop Parkinson’s and potential marker of disease progression, is quickly advancing, and scientists are learning more about this protein’s role in Parkinson’s disease (PD). Recently, researchers discovered how this…


New Gene Linked to Parkinson’s Disease

Tuesday, 21 June 2016

Researchers recently added to the list of Parkinson’s-associated genes when they identified mutations on TMEM230  linked to the disease. Discovery of this gene provides a new potential therapeutic target for PD treatment. A group of scientists searched for differences in…


Ask the MD: Head Trauma and Parkinson’s Disease

Monday, 20 June 2016

The possible connection between head trauma and Parkinson’s is illustrated — perhaps nowhere more prominently — by Muhammad Ali’s diagnosis of young-onset Parkinson’s disease (PD) following a career in boxing. Many have wondered whether repeated hits to the head caused his PD….


Connecting supporters directly with researchers

Thursday, 12 May 2016

Last Friday Shake It Up CEO, Ben Young hosted a research information session in Brisbane where supporters had the opportunity to hear directly from researchers at The University of Queensland. Associate Professor Trent Woodruff and Dr Richard Gordon shared their…


Maintaining momentum in the quest for a cure

Monday, 9 May 2016

It is true that Shake It Up has had a very significant period of Parkinson’s research funding announcements over the last couple of months. Whilst we are thrilled to share news of these projects with you, our supporters, we also…


Shake It Up and Parkinson’s Victoria working together

Wednesday, 20 April 2016

On Monday 11 April, Shake It Up Australia and Parkinson’s Victoria announced their firm commitment to work together in the area of research funding for the benefit of the entire Parkinson’s Community. In a challenging fiscal environment, the two organisations…