Shake It Up and The Michael J. Fox Foundation are on a roll! Today we share with you our commitment to fund another world class Australian research project – the fourth such announcement in four weeks! It comes less than 24 hours before World Parkinson’s Day – a day when we ask all in the community to shine a light on Parkinson’s and the need for more research.
This commitment is part of the over $1.6M committed to five Australian Parkinson’s research projects so far this financial year; making the Shake It Up / MJFF partnership the largest non-government funder of Parkinson’s research in Australia.
Help us to continue this work by joining us on World Parkinson’s Day as we Pause 4 Parkinson’s. You can host an event anytime in April or simply make a donation. Together we will find better treatments on the path to a cure.
Researcher: Nicolas Luke Dzamko, PhD
Institution: Neuroscience Research Australia
Grant Title: Fluorescence tagging of endogenous LRRK2 to enable in vivo imaging in mice and differentiated human IPS cells.
Grant Summary: The leucine-rich repeat kinase 2 (LRRK2) protein is emerging as an important player underlying Parkinson’s disease. Unfortunately, LRRK2 is also a large, complex and difficult to study protein. This study aims to generate a fluorescent version of the endogenous LRRK2 in mice and cells. The fluorescent LRRK2 will be much easier to measure. This will aid in determining where LRRK2 is expressed and if/how the expression of LRRK2 changes with Parkinson’s disease.
Cost: AUD $143,628
Having recently committed such large sums of money to new projects, Shake It Up must now generate additional revenue if we are to maintain our commitment.
To that end we are seeking to raise an additional $1M by the end of 2016 and we need your help.
Please contribute today so that we can maintain our pace in the quest for a cure.
About Nic DzmakoNic Dzamko works with Professor Glenda Halliday to understand the causes of Parkinson’s disease. In Particular Nic focuses on the leucine-rich repeat kinase 2 (LRRK2), the leading genetic cause of autosomal dominant Parkinson’s disease. Nic has a biomedical science degree with first class honours and a Chancellors letter of commendation from Flinders University of South Australia and a PhD from the University of Melbourne. Nic has trained at the Garvan Institute of Medical Research and at the MRC Protein Phosphorylation Unit in Dundee, Scotland.
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