Clinical Trials

Doctor and Patient

“Clinical trial participation sends the Parkinson’s community an invaluable message: There’s something you can do. Participating in research makes you an agent of change.”

Michael J. Fox

When you participate in research, you give something money can’t buy. Parkinson’s patients and their loved ones are eager to play an active role in finding the cure, and dozens of new clinical trials are launched each year. Yet challenges identifying participants too often mean that these studies finish late — or never really get started.

Today, 80 percent of trials fail to recruit enough volunteers within planned timelines. This slows research progress and deters funders from investing in Parkinson’s research. It is estimated that only 1 in 10 people with Parkinson’s participate in clinical trials. Yet in spite of the challenges, we know that this low participation rate belies the Parkinson’s community’s significant interest in stepping up.

Fox Trial Finder makes it easy for patients and their loved ones to find personalised potential trial matches based on specific individual criteria (i.e. location and medical history). You can connect with trial teams to learn more about participating, and stay alerted to future potential matches that arise as new trials start recruiting.

Click on the image below to create your Fox Finder profile


Clinical Trials Need You

  • 30% of all clinical trials fail to recruit a single person
  • 85% of clinical trials face delays due to limited participation
  • Fewer than 10% of Parkinson’s patients ever take part in trials, despite overwhelming interest in working with scientists to help speed treatment breakthroughs

About Fox Trial Finder

  • Fox Trial Finder (FTF) is a user-friendly Web site that connects volunteers with clinical trials.
  • The tool suggests trial matches that need someone specifically like you. It even alerts you when new trials that may be matches are added.
  • You can be matched to trials by answering as few as three questions, though the more information you provide, the better your results will be.
  • Your privacy is protected by industry-standard security protocols.
  • You don’t have to have Parkinson’s disease to sign up — many trials need control participants. Spread the word to your friends and family!

Trial Facts

  • There are many different types of Parkinson’s trials, including ones that test new drug compounds and devices (interventional trials) , ones that aim to better understand the disease (observational trials), and tests of non-pharmacological interventions such as acupuncture, exercise and even video gaming
  • Fewer than half of all trial participants ever receive a placebo
  • Participating in a trial should not interfere with your usual care
  • As a volunteer, you are protected by the patient’s bill of rights that allows you to end your participation in the trial at any point

Types of Clinical Trials

• Treatment trials test new treatments, new combinations of drugs, or new approaches to surgery or radiation therapy.
• Prevention trials look for better ways to prevent disease in people who have never had the ailment or to prevent a disease from returning. These approaches may include medicines, vitamins, minerals, vaccines, or lifestyle changes.
• Diagnostic trials are conducted to find better tests or procedures for diagnosing a disease or condition.
• Screening trials test the best way to detect certain diseases or health conditions.
• Quality-of-life trials, also known as supportive care trials, explore ways to improve quality of life for people with chronic illnesses.

Clinical Trial Phases

Phase I: Researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate safety, determine a safe dosage range, and identify side effects.

Phase II: The studied drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.

Phase III: The studied drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments and collect data that will allow the treatment to be used safely.

Phase IV: After a drug or treatment is on the market, this phase is used to delineate additional information, including its risks, benefits, and optimal use.


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