Genetics

New Research Confirms Role of LRRK2 in Immune Cells

Monday, 10 April 2017

Though associated with only a small percentage of total Parkinson’s cases, mutations of the LRRK2 gene are the greatest known genetic contributor to Parkinson’s disease (PD). Researchers are striving to understand the mechanisms of disease related to this mutation because…

Another Leap Forward for LRRK2 Development

Monday, 29 August 2016

Denali Therapeutics — a San Francisco biotech that launched last year focused on neurodegenerative diseases including Parkinson’s — recently announced it has licensed LRRK2 inhibitor compounds from Genentech. These drug candidates may address the dysfunction seen with LRRK2 mutations, the greatest…

New Gene Linked to Parkinson’s Disease

Tuesday, 21 June 2016

Researchers recently added to the list of Parkinson’s-associated genes when they identified mutations on TMEM230  linked to the disease. Discovery of this gene provides a new potential therapeutic target for PD treatment. A group of scientists searched for differences in…

genetic mutations

How Genetics Has Transformed Parkinson’s research

Monday, 8 February 2016

Over her career Tatiana Foroud, PhD, now director of the Hereditary Genomics Division at Indiana University, has seen the study of Parkinson’s genetics grow exponentially. In the latest podcast from The Michael J. Fox Foundation, she explains how this area…

Is Parkinson's Genetic. Register for the WEbinar with Professor Dominic Rowe and Professor Glenda Halliday

Webinar Series – Genetics & Parkinson’s

Saturday, 28 March 2015

Is Parkinson’s genetic? Only about 10 percent of Parkinson’s cases have been linked to a genetic cause. However, some genes may increase the risk of PD, some may impact the rate of progression and others may even protect people from…

Genetics and parkinson's disease

Is Parkinson’s Disease Genetic? Maybe…

Tuesday, 22 April 2014

Everyone in the Parkinson’s disease (PD) community likely has heard this question and asked it themselves. We say that PD is rarely caused by genetics, but what does that mean for those living with the disease today, their children and…

A Family Affair: The Genetics of Parkinson’s Disease

Monday, 4 March 2013

The below post is written by Genia Brin, mother of internet entrepreneur and Google Co-Founder Sergey Brin. Care of the Michael J Fox Foundation, Genia looks into how her family went about finding out if they were impacted by a…