Parkinson’s Research Project Title: Investigation of disease- and pathogen-specific immune dysfunction traits in human PBMCs

Principal Investigators:

Malú Tansey, PhD 

Nicolas Dzamko, PhD 

Institutions: University of Sydney and University of Florida

Study Rationale:

This is a supplemental proposal following previous funding where the team developed and optimised a sample collection and processing protocol with flow cytometry assays at University of Sydney and University of Florida (WHOPPA). This project will assess the contribution of immune dysfunction in LRRK2 and GBA1 mutation carriers, allowing the team to stratify patients and implement future personalised therapy approaches.